The authors created a consensus genome-scale model of CHO cell metabolism with 1,766 genes and 6,663 reactions describing metabolism and protein production during cell growth. Cell line-specific models for CHO-K1, CHO-S, and CHO-DG44 cells were also created and the integration of -omics data revealed amino acid auxotrophy bases in various cell lines.
We are excited to announce that the significantly improved Chinese hamster genome, CH PICR (GCF_00366804.1), along with its 2018 RefSeq annotation is now online. In addition, an updated RefSeq annotation for the CHO-K1 cell line is now available. Both can be searched (gene search and BLAST) and viewed on JBrowse. More information on the updated Chinese hamster genome can be found here.
New mRNA Expression Browser (Beta)
June 7, 2017
The browser (beta version) for the visualization of mRNA expression from CHO-K1 cells is now online. The data is from several published DNA-microarray or RNA-Seq experiments. The tutorial on how to use this browser can be found here.
Coming Soon!
March 10, 2017
Users will be able to visualize CHO cell mRNA expression data either from published DNA-microarray or RNA-Seq experiments via JBrowse. The visualized data will enable users to easily obtain gene expression levels and compare gene expression levels among different conditions.
Gene Search
Search the RefSeq Chinese Hamster and CHO-K1 assemblies
BLAST
BLAST sequences against Chinese Hamster or CHO-K1 genomes
Genome Viewer
View the annotated RefSeq Chinese Hamster or CHO-K1 genomes
Proteome Browser
Search the 2-D gel and shotgun datasets
Downloads
Useful Chinese Hamster publications and files
CH Genome Viewer
View the chromosome-sorted Chinese Hamster genome
Events
Previous Events
Mammalian Systems Biotechnology Workshop
Singapore
August 11 - August 12, 2016
This workshop will bring together globally eminent experts actively working in the Mammalian Systems Biotechnology field, in order to share and discuss state-of-the-art developments and their industrial applications.
The Cell Culture Engineering XV conference will bring together about 350 selected participants from top academic, industrial and governmental groups from all over the world.
The 251st ACS National Meeting & Exposition in San Diego, CA will convene from March 13 - 17, 2016 and the BIOT division will focus on the exchange of information among academic and industrial researchers regarding technology utilizing life-based systems to produce useful products and services.
