News
Updated chromosome-scale CH assembly and CH/CHO-K1 annotations
January 27, 2021
A significantly more continuous version of the Chinese hamster genome, CH PICRH (GCF_003668045.3), along with its 2020 RefSeq annotation is now on CHOgenome.org. Long-range scaffolding of the previous CH genome assembly was performed using high-throughput chromosome conformation capture (Hi-C) and now 97% of the genome is contained in 11 large scaffolds corresponding to the CH chromosomes. In addition, the updated 2020 RefSeq annotation for the CHO-K1 cell line is available. Both can be searched (gene search and BLAST) and viewed on JBrowse. More information on the most recent version of the Chinese hamster genome can be found here.
Updated CH assembly and CH/CHO-K1 annotations
May 1, 2019
We are excited to announce that the significantly improved Chinese hamster genome, CH PICR (GCF_00366804.1), along with its 2018 RefSeq annotation is now online. In addition, an updated RefSeq annotation for the CHO-K1 cell line is now available. Both can be searched (gene search and BLAST) and viewed on JBrowse. More information on the updated Chinese hamster genome can be found here.
New mRNA Expression Browser (Beta)
June 7, 2017
The browser (beta version) for the visualization of mRNA expression from CHO-K1 cells is now online. The data is from several published DNA-microarray or RNA-Seq experiments. The tutorial on how to use this browser can be found here.
2012 Bioprocess International Awards Ceremony
October 9, 2012
The international community's effort was recognized at the 2012 Bioprocess International Awards ceremony in Providence, RI, held on October 9th, 2012. CHOgenome.org was nominated as one of three finalists for the Upstream Collaboration of the Decade Award. "The Collaboration of the Decade Award recognizes industry alliances and collaborations whose innovative partnerships dramatically transformed stand-alone technologies. These collaborations result in overall process cost reduction while creating new, effective approaches to biopharmaceutical design, development, and manufacturing."
We are grateful and would like to recognize the support and engagement of the broad international community in the sequencing of CHO and related genomes to improve bioprocessing.