News

Updated chromosome-scale CH assembly and CH/CHO-K1 annotations

January 27, 2021

A significantly more continuous version of the Chinese hamster genome, CH PICRH (GCF_003668045.3), along with its 2020 RefSeq annotation is now on CHOgenome.org. Long-range scaffolding of the previous CH genome assembly was performed using high-throughput chromosome conformation capture (Hi-C) and now 97% of the genome is contained in 11 large scaffolds corresponding to the CH chromosomes. In addition, the updated 2020 RefSeq annotation for the CHO-K1 cell line is available. Both can be searched (gene search and BLAST) and viewed on JBrowse. More information on the most recent version of the Chinese hamster genome can be found here.

Updated CH assembly and CH/CHO-K1 annotations

May 1, 2019

We are excited to announce that the significantly improved Chinese hamster genome, CH PICR (GCF_00366804.1), along with its 2018 RefSeq annotation is now online. In addition, an updated RefSeq annotation for the CHO-K1 cell line is now available. Both can be searched (gene search and BLAST) and viewed on JBrowse. More information on the updated Chinese hamster genome can be found here.

New mRNA Expression Browser (Beta)

June 7, 2017

The browser (beta version) for the visualization of mRNA expression from CHO-K1 cells is now online. The data is from several published DNA-microarray or RNA-Seq experiments. The tutorial on how to use this browser can be found here.

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CHO-March 2012 Example Data

Spots Information

Spot No.	Symbol	Identification	NCBI Protein Accession	CHO Genome Database Link	CHO RefSeq Database Link
144	EGV96168	Glucosidase 2 subunit beta	gi\|344240065
313	EGV94255	78 kDa glucose-regulated protein	gi\|344238152
428	EGW10858	Heat shock cognate 71 kDa protein	gi\|344254754
492	EGW05785	Clusterin	gi\|344249681
638	EGW10391	Tubulin alpha-1A chain	gi\|344254287
720	EGW09077	Tubulin beta-7 chain	gi\|344252973
869	EGV98172	Calumenin	gi\|344242069
908	EGV93891	Eukaryotic initiation factor 4A-I	gi\|344237788
998	EGV95774	Actin, cytoplasmic 1	gi\|344239671
1098	EGW01943	Nuclear migration protein nudC	gi\|344245839
1346	EGW12488	Nascent polypeptide-associated complex subunit alpha, muscle-specific form	gi\|344256384
1658	EGW03571	Heme oxygenase 1	gi\|344247467
2098	EGW12933	Ferritin heavy chain	gi\|344256829